Hello Friends 🫠

It has been a long week at the incubator... Daphna and I have both been on service and otherwise busy with the launch of the Neonatal Network (N2). This meant another late night recording πŸ˜΅β€πŸ’«. But the papers this week were so interesting that we had a great time discussing this latest evidence. We reviewed the recently published article in the New England Journal of Medicine describing how using high flow nasal cannula during an intubation attempt could significantly increase the success rates of a first attempt. Daphna reviewed a paper from the Journal of Pediatrics that thoroughly reviewed the impact of oxygenation factors on the development of ROP in preterm infants. Some interesting data there. We also reviewed a JAMA Peds article from China πŸ‡¨πŸ‡³ that compared the use of nasal CPAP vs nasal IMV and nasal high frequency ventilation. This is something we are still no very familiar with so it was interesting to see how it compares to other modalities we are familiar with. We referenced a blog post from our friend Michael Narvey on nHFO that you can check out here: https://www.allthingsneonatal.com/2015/12/19/high-frequency-nasal-ventilation-what-are-we-waiting-for/ We also reviewed an article from Holland πŸ‡³πŸ‡± comparing open bay nicu setup and single room on short term morbidity and mortality. Finally, one last paper from Australia πŸ‡¦πŸ‡Ί / New Zealand πŸ‡³πŸ‡Ώ looking at the collective use of non invasive ventilation in term infants.... some very interesting findings.

We hope you enjoy this episode!

Cheers ✌️


Nasal High-Flow Therapy during Neonatal Endotracheal Intubation | NEJM
Original Article from The New England Journal of Medicine β€” Nasal High-Flow Therapy during Neonatal Endotracheal Intubation
Oxygenation factors associated with retinopathy of prematurity in extremely low birth weight infants
To study characteristics of oxygenation during the first two postnatal months andcorrelation with the occurrence and severity of retinopathy of prematurity (ROP) amongextremely low birth weight infants.
NHFOV vs NCPAP vs NIPPV as Postextubation Support in Preterm Neonates
This randomized clinical trial compares the total duration of invasive mechanical ventilation, need for reintubation, and ventilator-free days associated with noninvasive high-frequency oscillatory ventilation, nasal continuous positive airway pressure, and nasal intermittent positive pressure...
Comparison of neonatal morbidity and mortality between single-room and open-bay care: a retrospective cohort study
Objective In response to the increasing focus on family-centred care, neonatal intensive care unit (NICU) environments have gradually shifted towards the single-room design. However, the assumed benefits of this emerging design remain a subject of debate. Our goal was to evaluate the impact of singl…
Trends in the use of non-invasive respiratory support for term infants in tertiary neonatal units in Australia and New Zealand
Objective To determine whether the use of non-invasive respiratory support, such as continuous positive airway pressure and nasal high flow, to treat term infants in Australian and New Zealand tertiary neonatal intensive care units (NICUs) has changed over time, and if so, whether there are parallel…