Hello friends 👋

Journal club is BACK!!!

We have many many articles to go over today. Most notably the recent publication by the neonatal research network in the New England Journal of Medicine looking at the use of prophylactic hydrocortisone to improve BPD-free survival. We even had the pleasure to ask the lead author Dr. Kristi Watterberg about her thoughts on how to interpret the data. She will also join us for a full interview to be released on April 17th. Look out for this interview.

Daphna reviews some interesting articles about provider concordance regarding goals of care discussion in the nicu and reviews an amazing QI project aimed at reducing length of stay by improving time to full oral feeds.

We also chat about probiotics to reduce NEC, use of glycerin suppositories and whether or not they are associated with increased rates of NEC in preterm infants, and review some interesting neurodevelopmental outcomes from our scandinavian colleagues. Enjoy!


Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia | NEJM
Original Article from The New England Journal of Medicine — Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia
Provider concordance regarding elements of goals-of-care discussions in neonatal intensive care - PubMed
Provider concordance regarding elements of goals-of-care discussions in neonatal intensive care
Glycerin Suppositories and Enemas in Premature Infants: A Meta-analysis
BACKGROUND AND OBJECTIVES. Premature infants are often given glycerin suppositories or enemas to facilitate meconium evacuation and the transition to enteral feeds. We reviewed the best-available evidence for the use of glycerin suppositories and enemas in premature infants.METHODS. We searched MEDL…
Neurodevelopmental disorders and somatic diagnoses in a national cohort of children born before 24 weeks of gestation - PubMed
Most children born before 24 weeks had neurodevelopmental disorders and/or additional somatic diagnoses in childhood and were referred to habilitation services. Clinicians should be aware of the multiple health and developmental problems affecting these children. Resources are needed to identify the…
Predictive Ability of 10-Minute Apgar Scores for Mortality and Neurodevelopmental Disability
OBJECTIVE. To test the hypothesis that an Apgar score at 10 minutes is independently predictive for death or moderate or severe disability.METHODS. A secondary analysis of the Optimizing Cooling Trial (NCT01192776) including 347 infants with ≥36 weeks’ gestational age at birth and hypoxic-ischemic e…
Improving Time to Independent Oral Feeding to Expedite Hospital Discharge in Preterm Infants
BACKGROUND AND OBJECTIVES. Achievement of independent oral feedings remains the most common barrier to discharge in preterm infants. Early oral feeding initiation may be associated with a lower postmenstrual age (PMA) at independent oral feeding and discharge. In preterm infants born between 25 and…
Bifidobacterium longum subsp. infantis EVC001 Administration Is Associated with a Significant Reduction in the Incidence of Necrotizing Enterocolitis in Very Low Birth Weight Infants
To assess the effects of Bifidobacterium longum subsp. infantis EVC001 (B infantisEVC001) administration on the incidence of necrotizing enterocolitis (NEC) in preterminfants in a single level IV neonatal intensive care unit (NICU).